Migraine with aura (Visual Aura)

Migraine is a surprisingly common disorder. It occurs in up to 8% of men and over 25% of women, its occurence peaking in ages 30 to 50 years.

Migraine is a complex and interesting condition in which there are a number of possible symptoms sharing a common cause. The usual syndromes are as follows:

Common Migraine: One-sided headache, usually throbbing, may be severe, with nausea, and sensitivity to light and sound. Officially, Migraine without Aura.

Classic Migraine: Begins with visual symptoms of flashing lights or a sensation of watery movement that starts in one corner of vision and expands to cover half or more of vision, usually with part of the image missing, as in the illustrations. This “aura” phase lasts from 15 minutes to hours, followed by the headache phase as described above. Officially, Migraine with Aura.

Ocular Migraine: Visual symptoms of aura, but not followed by headache. Officially, Typical Aura without Headache.

Progression of Migraine with visual aura

Rizelium (Flunarizine Advert) for migraine

Pharma Ads Collection Vol: 1

Rizelium (Flunarizine) Advert

Migraine is among the 10 most disabling disorders worldwide. Besides acute attack treatment, drug prophylaxis of migraine is important in order to improve the quality of life. 

The drugs of first choice are β-blockers, flunarizine, valproic acid and topiramate and, in the US, amitriptyline is also grouped among the first-choice drugs. 

Drugs of second choice, with less efficacy or poorer evidence, are venlafaxine, gabapentin, naproxen, butterbur root, vitamin B 2 and magnesium. The potential side effects are considered when choosing the appropriate prophylactic drug. All drugs used in migraine prophylaxis have been detected by chance and not by pathophysiological considerations. In the future, drugs developed on the basis of the current

knowledge of migraine pathophysiology will hopefully be more effective.

Expert Opin. Pharmacother. (2008) 9(15):2565-2573

Brand: Rizelium (Bangladesh) 
Generic: Flunarizine
Positioning statement: An idea prophylactic agent in migraine 
Target Customer: Neurologist, Ophthalmologist, ENT