Migraine is among the 10 most disabling disorders worldwide. Besides acute attack treatment, drug prophylaxis of migraine is important in order to improve the quality of life.
The drugs of first choice are Ī²-blockers, flunarizine, valproic acid and topiramate and, in the US, amitriptyline is also grouped among the first-choice drugs.
Drugs of second choice, with less efficacy or poorer evidence, are venlafaxine, gabapentin, naproxen, butterbur root, vitamin B 2 and magnesium. The potential side effects are considered when choosing the appropriate prophylactic drug. All drugs used in migraine prophylaxis have been detected by chance and not by pathophysiological considerations. In the future, drugs developed on the basis of the current
knowledge of migraine pathophysiology will hopefully be more effective.
Expert Opin. Pharmacother. (2008) 9(15):2565-2573
Brand: Rizelium (Bangladesh)
Generic: Flunarizine
Positioning statement: An idea prophylactic agent in migraine
Target Customer: Neurologist, Ophthalmologist, ENT
Generic: Flunarizine
Positioning statement: An idea prophylactic agent in migraine
Target Customer: Neurologist, Ophthalmologist, ENT
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